Current Research Studies

Fisher Center members are involved in several genetic counseling research projects, as listed below.

If you have questions about these studies, please contact us at 877-687-2720 (toll-free) or fisher.research@georgetown.edu.

To make an appointment for clinical genetic counseling and testing for hereditary cancer risk at MedStar Georgetown Lombardi Comprehensive Cancer Center, please call (202) 444-0023 or email GUH-LombardiGenetics@medstar.net.


Adjuncts to Genetic Counseling and Testing

Genetic Counseling and Testing in Women

Genetic Counseling and Testing in Families

Genetic Counseling Studies in Latinx Populations


Adjuncts to Genetic Counseling and Testing


Parent Communication Study (PCS) IV: Improving Genetic Counseling for BRCA+ Mothers

  • Participants are mothers with a BRCA1 or BRCA2 mutation who have at least one child between 13-24 years old
  • Randomized clinical trial of an educational workbook or an educational workbook plus telephone sessions with a parent coach
  • The purpose of this study is to help mothers make more informed choices about talking with children about hereditary breast/ovarian cancer, and to provide mothers with information and support for their children and families
  • Participating sites: Georgetown Lombardi Comprehensive Cancer Center, Memorial Sloan Kettering Cancer Center, Inova Schar Cancer Institute, Dana-Farber Cancer Institute
  • Funded by the National Institutes of Health/National Cancer Institute
  • PIs: Dr. Kenneth Tercyak and Ms. Beth N. Peshkin

Genetic Counseling and Testing in Women


Achieving Cancer Equity through Identification, Testing, and Screening (ACE-ITS)

  • Quality improvement project to address breast cancer disparities in the District of Columbia (DC) metropolitan area
  • The project focuses on encouraging women who have had a mammogram through the Capital Breast Care Center (CBCC) to continue to have regular mammograms and identifying women who would be eligible for genetic counseling and testing
  • Participating site: Georgetown Lombardi Comprehensive Cancer Center
  • Funded by Pfizer and the American Cancer Society
  • PIs: Drs. Chiranjeev Dash and Suzanne O’Neill; Community Partners: Ms. Thelma D. Jones (Thelma D. Jones Breast Cancer Fund) and Ms. Ify Nwabukwu (African Women’s Cancer Awareness Association)

Genetic Counseling and Testing in Families


Peers and Cancer Empowerment (PeACE)

  • Randomized clinical trial evaluating the impact and efficacy of a peer support intervention for young female blood relatives (aged 21-30) of male or female BRCA1/2 carriers
  • Participants receive either three sessions of a telephone-based peer counseling program or are navigated to receive community-based peer support
  • The purpose of the study is to offer support, train young women in coping strategies for health-related stress and support decision making and problem solving
  • Participating sites: Georgetown Lombardi Comprehensive Cancer Center, Memorial Sloan Kettering Cancer Center
  • Funded by the National Institutes of Health/National Cancer Institute
  • PIs: Drs. Suzanne O’Neill and Kenneth Tercyak

CASCADE: CAncer Susceptibility Counseling And DEcisions

  • Participants are untested men and women from families in which a BRCA1 or BRCA2 mutation has been identified
  • Randomized clinical trial to develop and evaluate delivery of a proactive web-based genetic education intervention plus streamlined telephone counseling
  • Participating sites: Georgetown Lombardi Comprehensive Cancer Center, George Washington Cancer Institute, Geisinger Clinic, Inova Schar Cancer Institute
  • Funded by the National Institutes of Health/National Cancer Institute
  • PI: Dr. Marc Schwartz

Genetic Counseling Studies in Latinx Populations


Testing a Hereditary Breast and Ovarian Cancer Video in At-Risk Latinas

  • Randomized clinical trial among Latina women at-risk of hereditary breast and ovarian cancer
  • Participants receive either a culturally targeted video or a fact sheet about hereditary breast and ovarian cancer  
  • Participants have the option of obtaining free telephone genetic counseling
  • Participating sites: Nueva Vida, Capital Breast Care Center, Arlington Free Clinic, Virginia Commonwealth University (La Casa de la Salud)
  • Funded by the National Institutes of Health/National Cancer Institute
  • PI: Dr. Alejandra Hurtado de Mendoza

ÁRBOLES Familiares (Family Tree) Training Program: Assessing the Risk of Breast Cancer through Outreach to Latinas with Education and Support

  • Program to train community health educators, promotoras, community health workers and patient navigators who work with the Latinx community
  • Trainees attend a 2.5 day in-person workshop followed by 6 online sessions
  • Curriculum enhances trainees’ “referral-level competence” to identify Latinas at high risk of hereditary breast and ovarian cancer and navigate them to appropriate genetic services
  • Funded by the National Institutes of Health/National Cancer Institute
  • PIs: Drs. Kristi Graves (Georgetown) and Susan Vadaparampil (Moffitt Cancer Center; Tampa, FL)

ÁRBOLES LATIN AMERICA

  • Physicians, community health navigators, and individuals with breast or ovarian cancer diagnoses in Guatemala, Mexico, and Colombia
  • Participants will complete an hour-long individual interview about their knowledge of and experiences with HBOC genetic testing and genetic services in their country of residence and provide suggestions to adapt the ÁRBOLES Familiares program to their country and population
  • Assess interest and feasibility of implementing existing ÁRBOLES Familiares training in Guatemala, Mexico, and Colombia. Assess the current knowledge of genetic counseling and testing services and HBOC in Guatemala, Mexico, and Colombia.
  • Participating site: Georgetown University
  • Funded by the Global Health Initiative (Georgetown University)
  • PIs: Drs. Kristi Graves and Alejandra Hurtado de Mendoza

If you have questions about these studies, please contact us at 877-687-2720 (toll-free) or fisher.research@georgetown.edu.

To make an appointment for clinical genetic counseling and testing for hereditary cancer risk at MedStar Georgetown Lombardi Comprehensive Cancer Center, please call (202) 444-0023 or email  GUH-LombardiGenetics@medstar.net.

Updated on 8/23/2022